Red 3 food dye causes cancer
Static snapshot — vote, comment, and submit papers on the live app.
Open in Live App →- Not Tested in Humans
Estrogenic and DNA-damaging activity of Red No. 3 in human breast cancer cells.
Published 1997Reviewer Insight6/7/2026This lab study found that Red No. 3 food dye can stimulate the growth of breast cancer cells in a dish and shows signs of damaging DNA in those cells.
- The experiments used cancer cells in a dish, not real people — what happens in a lab dish often doesn't translate to the human body
- Only 3 cell samples were used per experiment, which is far too few to draw reliable conclusions
- The p53 response used to suggest DNA damage can also be triggered by non-damaging stresses like low oxygen
- The two cell types compared to cancer cells were biologically different in multiple ways, not just in their estrogen receptors, making the comparison less clean than it appears
- The authors themselves say more studies in living organisms are needed before any conclusion about cancer risk in people can be drawn
- Awaiting Review
The Promoting Effects of Food Dyes, Erythrosine (Red 3) and Rose Bengal B (Red 105), on Thyroid Tumors in Partially Thyroidectomized N‐Bis(2‐hydroxypropyl)‐ nitrosamine‐treated Rats
Published 1988
Snapshot built: 2026-06-19